Presiding over a company with a market value of $143 billion apparently gives Silicon Valley’s most famous billionaires a good sense of humor – and a case of corporate potty mouth.

Senior executives at Google Inc. launched their annual April Fools’ Day prank Sunday, posting a link on the company’s home page to a site offering consumers free high-speed wireless Internet through their home plumbing systems.

Code-named “Dark Porcelain,” Google said its “Toilet Internet Service Provider” (TiSP) works with Microsoft Corp.’s new Windows Vista operating system. But sorry – septic tanks are incompatible with the system’s requirements.

The gag included a mock press release quoting Google co-founder and president Larry Page, a step-by-step online installation manual, and a scatological selection of Frequently Asked Questions. On some Google sites, the company’s official logo – a multicolored “Google” that changes according to the season and on holidays – substituted a commode for the second “g.”

“There’s actually a thriving little underground community that’s been studying this exact solution for a long time,” Page said in the facetious statement. “And today our Toilet ISP team is pleased to be leading the way through the sewers, up out of your toilet and – splat – right onto your PC.”

Marissa Mayer, a Google vice president, called TiSP a “breakthrough product, particularly for those users who, like Larry himself, do much of their best thinking in the bathroom.”

TiSP is the latest April Fools joke at the Mountain View, Calif.-based company, where hijinks pervade cubicles all year long. In blogs, Google employees joke about the recent injection of green dye into milk in the cafeteria, while another talks about zany underlings filling the vice president of engineering’s office with sand.

Eric Raymond, a software developer in Malvern, Pa., and author of the New Hacker’s Dictionary, said TiSP nailed several important tenets of hacker humor.

The concept of free wireless access parallels a legitimate, four-year deal between Google and EarthLink Inc. to provide free wireless Internet service throughout San Francisco starting in early 2008.

Source: Forbes.com

Target Health is pleased to announce that we now represent 20 companies at FDA from all over the world and the US. Countries include England, France, Germany, Israel, Korea, Switzerland and Turkey. We recently prepared and submitted a PMA including an eCopy, and are preparing an eCTD, to be submitted shortly. A special protocol assessment went in this week and last month. We were at FDA 3 times, including a pre-NDA meeting. We have been responsible for 7 orphan drug request approved submissions and multiple IND/IDE in very diverse indications including, but not limited to: Cardiology (IDE; PMA), Cellular Products (IND, CBER), Dermatology (IND; NDA), Gastroenterology (IND), HIV/AIDS (IND), Men’s Health (IND), Metabolism (IND), Oncology (IND), Ophthalmology (IND, NDA), Oral Care (PMA) and Women’s Health (IDE; IND; 3 NDA’s). Glen Park, PharmD, who has been key to growing this department, runs our Clinical and Regulatory operation with Mary Shatzoff, Fredy Varela and Vanessa Hays. Collaborating with Dr. Park is Dr. Jules T. Mitchel, President of Target Health.

This year, we expect 3 products to be sumitted to FDA for marketing clearance (1 NDA, 1 BLA and 1 PMA, submitted) for which we did data management. For the NDA and PMA we also did monitoring, statistics, medical writing and reguatory affairs.

For more information, please contact Dr. Jules T. Mitchel.

In a larger sense, social cognition is an extreme example of a broader issue in biology of mind, and that is social interaction in general. Even here we are beginning to make some rather remarkable progress. Cori Bargmann, a geneticist at the Rockefeller University, has studied two variants of a 1) ___ called C elegans, that differ in their feeding pattern. One variant is 2) ___ and seeks its food alone; the other is social and forages in groups. The only difference between the two is one 3) ___ acid in an otherwise shared receptor protein. If you move the 4) ___ from a social worm to a solitary worm, it makes the solitary worm social. This is one of several examples in which changing a single gene 5) ___the social behavior of an animal. Source: In Search of memory: The Emergence of a New Science of Mind by Eric R. Kandel